Urokinase Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
Urokinase
Enzyme
Urokinase
Species
Human
Synonyms
PLAU, ATF, BDPLT5, QPD, UPA, URK, u-PA, plasminogen activator
Scientific Information
P00749 (https://www.uniprot.org/uniprotkb/P00749)
Assay Properties
Substrates
Fluorogenic peptide Bz-b-Ala-Gly-Arg-AMC AcOH, 10 µM
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 (nM) |
|---|---|
| Gabexate Mesylate | 27.2 |
Screening Location
Malvern, PA, USA
Further Information
More information can be found on our website Protease Assays
Reference compound inhibition of Urokinase
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