PROTEASE PROFILING & HTS

Protease Services Available:

  • Larger scale HTS;
  • Large scale single dose, duplicate profiling;
  • IC50 profiling — 10 dose with curve fitting;
  • Ki determination;
  • Custom Assay development;
  • Research collaboration.

RBC offers protease assays in both HTS and IC50 format. An HTS screen of 20,000 compounds against one protease costs as little as $25,000. IC50's can be priced as low as $20 each on an order of 100 compounds against one protease. For more information on RBC protease screening, or for a free price quote, call 1-877-347-2368 or email sales@reactionbiology.com

PROTEASES

(Click on highlighted names for PDF's)
Activated Protein C
ADAM-10
ADAM-12
ADAM-8
ADAM-9
Aminopeptidase A
Aminopeptidase M
Angiotensin-converting enzyme(ACE)
BACE 1
Calpain
Carboxypeptidase A
Carboxypeptidase B
Carboxypeptidase E
Carboxypeptidase G
Carboxypeptidase N
Caspase1
Caspase3
Caspase4
Caspase5
Caspase6
Caspase7
Caspase8
Caspase9
Caspase10
Caspase14
Cathepsin A
Cathepsin B
Cathepsin C
Cathepsin D
Cathepsin E
Cathepsin F
Cathepsin H
Cathepsin K
Cathepsin L
Cathepsin P
Cathepsin S
Cathepsin V
Cathepsin Z
Chymase
Chymotrypsin
Complement activated C1r
Complement activated C1s
Dipeptidyl peptidase IV (DDP-IV)
Elastase
Factor VIIa-Tf
Factor Xa
Factor XIa
Furin
Glutamate Carboxypeptidase II
Granzyme A
Granzyme B
Hepatitis C virus NS3/4A protease
Hepatocyte Growth Factor Activator (HGF-A)
HIV protease
Human CaaX protease (hRCE1)
Kallikrein
Kallikrein 3
Kallikrein 4
Kallikrein 5
Kallikrein 8
MMP1
MMP2
MMP3
MMP7
MMP9
MMP12
MMP13
MMP14
Papain
Pepsin
Plasmin
Proteinase A
Proteinase K
Renin
TACE
Thrombin
Tissue Plasminogen Activator (tPA)
Trypsin
Tryptase
Urokinase

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