G9a-GLP
DESCRIPTION:
In vivo, a heterodimeric complex of the related SET-domain histone methyltransferases (HMTs) G9a and GLP is the major source of mono- and dimethylated histone H3K9 in euchromatin, marks associated with recruitment of HP1, DNA methylation and gene silencing. Per mole of G9, GLP or (G9a + GLP), this equimolar mixture displays activity well in excess of G9a alone, similar to the more active GLP, suggesting a significant degree of heterodimer formation.
ACCESSION
#: NM_006709, NM_024757
UNIPROT LINK
INCLUDES
AMINO ACIDS: G9a 786-1210, GLP 894-1298
TAG(S):
N-terminal GST-tag on both
MW:
80.0 kDa/80.0 kDa
EXPRESSION SYSTEM: E. coli
SUPPLIED
AS:Solution of purified recombinant proteins in 25.4 mM Na2HPO4/NaH2PO4, pH 7.4, 137 mM NaCl, 2.7 mM KCl, 3 mM DTT, 30% (w/v) glycerol.
STORAGE: -80°C, aliquot and snap-freeze after
first use.
Product Data Sheet
Cat. #:
HMT-11-104
Size: 50 µg
Price: $325.00
Substantial Discounts Available on Bulk Quantities
TO ORDER OR REQUEST A
QUOTE:
Call 877-347-2368 OR EMAIL
sales@reactionbiology.com
RBC Can Also Profile/Screen G9a-GLP for You!