SMYD2
DESCRIPTION:
SMYD2 has been described as a histone H3 (H3K4, H3K36), p53 (p53K370) and Rb (retinoblastoma; RbK860) lysine methyltransferase, although RBC finds this recombinant SMYD2 preparation to be far more active in vitro with recombinant histone H4 than with histone H3, an H3(1-21) peptide, an H4(1-21) peptide, core histones or recombinant p53. SMYD2 is frequently overexpressed in esophageal squamous cell carcinoma (ESCC) and SMYD2 knockdown inhibits the proliferation of SMYD2-overexpressing ESCC cell lines.
ACCESSION
#: NM_020197
UNIPROT LINK
INCLUDES
AMINO ACIDS: 2-433 (C-term.)
TAG(S):
N-terminal His-tag
MW:
52 kDa
EXPRESSION SYSTEM: E. coli
SUPPLIED
AS: Solution of purified recombinant protein in 20 mM Tris/HCl, pH 8.0, 120 mM NaCl, 1 mM TCEP, 1 µM
ZnCl2, 10% (w/v) glycerol
STORAGE: -80°C, aliquot and snap-freeze after
first use.
Product Data Sheet
Cat. #:
HMT-11-110
Size: 50 µg
Price: $325.00
Substantial Discounts Available on Bulk Quantities
TO ORDER OR REQUEST A
QUOTE:
Call 877-347-2368 OR EMAIL
sales@reactionbiology.com
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