SUV39H2

DESCRIPTION:  Along with its close homolog, SUV39H1, SUV39H2 is responsible for the transcriptionally repressive modification, H3K9me3, in heterochromatin. Mice deleted in both SUV39H2 and SUV39H1 have elongated telomeres, implying a role for these enzymes and H3K9 methylation in regulation of telomere length. Polymorphisms in the human SUV39H2 gene have been associated with complications of type I diabetes and lung cancer risk.

ACCESSION #: NM_001193424

UNIPROT LINK

 

INCLUDES AMINO ACIDS: 48-410

TAG(S): N-terminal fusion protein with a C-terminal His-tag

MW: 98.2 kDa

EXPRESSION SYSTEM: E. coli


SUPPLIED AS: Solution of purified recombinant protein in 50 mM Tris/HCl, pH 8.0, 137 mM NaCl, 5 mM MgCl2, 4 mM DTT, 20% (v/v) glycerol

STORAGE: -80°C, aliquot and snap-freeze after first use.

Product Data Sheet

 

Cat. #: HMT-11-112            

Size: 50 µg               

Price: $299.00

 

Substantial Discounts Available on Bulk Quantities

 

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RBC Can Also Profile/Screen SUV39H2 for You!