News/Publications

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Customer Publication: November 17, 2011 - Catalog of Effects of Kinase Inhibitors May Aid Development of Anti-Cancer Drugs

Customer Publication: October 31, 2011 - Reaction Biology Corporation Unveils Largest Kinase Profiling Data Set in Nature Biotechnology Publication

Customer Publication: October 20, 2011 - Reaction Biology Now Offers Recombinant Methyltransferases to Complement Its Existing Epigenetic Services

Customer Publication: June 2011 - Identification of STK33 Kinase Inhibitors

Customer Publication: April 2011 - Oxime Amides as a Novel Zinc Binding Group in Histone Deacetylase Inhibitors: Synthesis, Biological Activity, and Computational Evaluation

Customer Publication: December 2010 - Suppression of inflamation by a synthetic histone mimic

Customer Publication: September, 2010 - A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells

RBC News: August 11, 2010 - Reaction Biology Receives NCI Grant Award for Epigenetic Platform

Customer Publication: July, 2010 - Rational Design and Simple Chemistry Yield a Superior, Neuroprotective HDAC6 Inhibitor, Tubastatin A

Customer Publication: July, 2010 - The Bruton tyrosine kinase inhibitor PCI-327 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy

Customer Publication: March, 2010 - Vorinostat-Like Molecules as Structural, Stereochemical, and Pharmacological Tools

Customer Publication : January, 2010 - In VivoStructure-Activity Relationship Study of Dorsomorphin Analogues Identifies Selective VEGF and BMP Inhibitors

RBC Publication : October, 2009 - Kinase assays for drug discovery and development

Customer Publication : October, 2009 - Identification of a series of substituted 2-piperazinyl-5-pyrimidylhydroxamic acids as potent histone deacetylase inhibitors

Customer Publication : 2009 - Azetidinones as Zinc-Binding Groups to Design Selective HDAC8 Inhibitors

Customer Publication : 2009 - Exploring bis-(indolyl)methane moiety as an alternative and innovative CAP group in the design of histone deacetylase (HDAC) inhibitors

Customer Publication : 2009 - N-Hydroxy-(4-oxime)-cinnamide: A versatile scaffold for the synthesis of novel histone deacetilase (HDAC) inhibitors

Customer Publication : 2009 - Grassystatins A-C from Marine Cyanobacteria, Potent Cathespsin E Inhibitors That Reduce Antigen Presentation

Customer Publication : September, 2009 - Cellular inhibition of Chk2 kinase and potentialation of camptothecins and radiation by the novel Chk2 inhibitor PV1019

Customer Publication : August, 2009 - Design, synthesis, screening, and molecular modeling of a new series of ROS1 receptor tyrosine kinase inhibitors

Customer Publication : June, 2009 - Design, synthesis and biological evaluation of new potent and hightly selective ROS1-tyrosine kinase inhibitor

Customer Publication : April, 2009 - Synthesis, Activity, and Pharmacophore Development for Isatin-B-thiosemicarbazones with Selective Activity toward Multidrug-Resistant Cells

Customer Publication : March, 2009 - Benzo[e]pyridoindoles, novel inhibitors of the aurora kinases

Customer Publication : March, 2008 - - Characterization of Chemical Libraries for Luciferase Inhibitory Activity

RBC Publication : 2008 - The challenge of selecting protein kinase assays for lead discovery optimization

RBC Publication : July, 2006 - Chemical microarray: a new tool for drug screening and discovery

RBC News : June 20, 2006 - Reaction Biology Corp Awarded NIH SBIR Grant for Kinase Radioisotope Microarray Screening Development

RBC News : June 1, 2006 - Key Organics Ltd and Reaction Biology Corp Announce New Library Screening Format

RBC News : March 13, 2006 - Reaction Biology Corporation Awarded NIH R01 Screening Roadmap Grant for Microarray Screening Development

RBC Publication : June, 2006 - Innovative chemical compound microarrays for drug screening

RBC Publication : 2006 - Biochemical Microarrays for Studying Chemical Biology Interaction: DiscoveryDottm Technology

RBC Publication : 2006 - Microarrays for the Functional Analysis of the Chemical-Kinase Interactome

RBC Publication : November, 2005 - Nanoliter Homogenous Ultra-High Throughtput Screening Microarray for Lead Discoveries and IC50 Profiling

RBC News : August 29, 2005 - Reaction Biology Corporation and Key Organics Ltd Announce Drug Discovery Collaboration

RBC News : August 9, 2005 - Reaction Biology Corporation Awarded Phase II SBIR Grant for Drug Discovery

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