Protease Profiling & HTS

Protease Services Available:

Larger scale HTS;
Large scale single dose, duplicate profiling;
IC50 profiling — 10 dose with curve fitting;
Ki determination;
Custom Assay development;
Research collaboration.

RBC offers protease assays in both HTS and IC50 format. An HTS screen of 20,000 compounds against one protease costs as little as $25,000. IC50's can be priced as low as $20 each on an order of 100 compounds against one protease. For more information on RBC protease screening, or for a free price quote, call 1-877-347-2368 or 1-610-722-0247 or email sales@reactionbiology.com.

Proteases

(Click on highlighted names for PDFs)

Activated Protein C
ACE1
ACE2
ADAM-9
ADAM-10
BACE 1
Calpain
Caspase 1
Caspace 2
Caspase 3
Caspase 4
Caspase 5
Caspase 6
Caspase 7
Caspase 8
Caspase 9
Caspase 10
Caspace 11
Caspase 14
Cathepsin B
Cathepsin C
Cathepsin D
Cathepsin E
Cathepsin G
Cathepsin H
Cathepsin K
Cathepsin L
Cathepsin S
Cathepsin V
Cathepsin Z
Chymase
Chymotrypsin
Complement activated C1s
Dipeptidyl peptidase IV (DDP-IV)
Dipeptidyl peptidase VIII (DPPVIII)
Dipeptidyl peptidase IX (DPPIX)
Elastase
Factor VIIa
Factor Xa
Factor XIa
Furin (Special order only)
Granzyme B
Hepatitis C virus NS3/4A protease
HIV protease
Kallikrein
Kallikrein 5
Kallikrein 8
Kallikrein 12
Kallikrein 13
Kallikrein 14
MMP 1
MMP 2
MMP 3
MMP 7
MMP 8
MMP 9
MMP 10
MMP 12
MMP 13
MMP 14
Papain
Plasma Kallikrein
Plasmin
Proteinase A
Proteinase K
Renin (Special order only)
TACE
Thrombin
Tissue Plasminogen Activator (tPA)
Trypsin
Tryptase
Urokinase