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Reader Domain Proteins
-Larger scale HTS
-Large scale single dose, duplicate profiling
-IC50 profiling — 10 dose with curve fitting
-Ki Determination
-Custom Assay development
Phosphatase enzymes remove a phosphate group from their substrate by hydrolysing phosphoric acid monoesters into a phosphate ion and a molecule with a free hydroxyl group. The addition of a phosphate group may activate or de-activate an enzyme (e.g., kinase signalling pathways[7]) or enable a protein-protein interaction to occur (e.g., SH2 domains [8]); therefore phosphatases are integral to many signal transduction pathways.


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With the largest functional kinase activity assay panel in the industry, RBC provides kinase, epigenetic, and other profiling services to over 750 companies worldwide. RBC specializes in custom assay conditions, high quality reproducible data, and outstanding service.

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