customer service
Reader Domain Proteins

Protease Assays

Currently, there are eight approved compounds for the treatment of HIV infections that are in the class known as protease inhibitors. Of all classes of HIV medications, the protease inhibitors are the most complex in terms of pharmacokinetics, drug interactions and dosing changes based on those interactions. In addition to HIV, protease inhibitors have been approved for treatment of Hepatitis C, ACE inhibitors, are being studied in relation to Alzheimers, Type II diabetes, and other indications. RBC offers 75 protease assays in both HTS and IC50 format.

Reaction Biology currently offers the following services for protease assays:

  • Larger scale HTS
  • Large scale single dose, duplicate profiling
  • IC50 profiling — 10 dose with curve fitting
  • Ki Determination
  • Custom Assay development


With the largest functional kinase activity assay panel in the industry, RBC provides kinase, epigenetic, and other profiling services to over 750 companies worldwide. RBC specializes in custom assay conditions, high quality reproducible data, and outstanding service.

Reaction Biology Corp. 1 Great Valley Parkway, Suite 2 Malvern, PA 19355 1-877-347-2368 or 610-722-0247
Reaction Biology Corp. © 2016 all rights reserved.