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Reader Domain Proteins

Two-Electrode Voltage Clamp Assay

The TEVC platform is used for assaying channel activity in the Xenopus oocyte expression system. One of the major advantages is that there is no need for the generation of a stable cell line and the oocytes are relatively cheap and easy to maintain. This is a low throughput platform most suitable for confirming hits or for use in lead optimization. Both voltage-gated and ligand-gated channels can be tested in this system.

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two-electrode voltage clamp assay

With the largest functional kinase activity assay panel in the industry, RBC provides kinase, epigenetic, and other profiling services to over 750 companies worldwide. RBC specializes in custom assay conditions, high quality reproducible data, and outstanding service.

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