Target Information
Cell Catalog#
LLC-2111
GPCR Name
Human Gastrin/cholecystokinin type B receptor
Gene Name
CCKBR
GPCR Sub Family
Cholecystokinin receptors
Coupling Partner
Gαq
Uniprot Number
P32239 (https://www.uniprot.org/uniprotkb/P32239/entry)
Cell Type
HEK293/β-arrestin-2 stable cell line
Assay Information
Assay Principle
The calcium flux agonist assay measures agonist-triggered, real-time calcium flux via activation of transiently transfected CCKBR in HEK293/β-arrestin-2 stable cell line.
Assay Type
Cell-based functional assay
Functional Mode
Agonist
Assay Readout
Fluorescence
Reference Compound EC50
Screening Location
Malvern, PA, USA
Further Information
More information can be found on our website GPCR Assay and Profiling Services
Representative dose–response curve of reference agonist for CCKBR
