ABL2/ARG Kinase Assay Service

Activity-based ABL2/ARG kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview
CAT#
ABL2
Enzyme
Human ABL2
HGNC
ABL2
Synonym
ABLL, ARG
Substrates
Peptide substrate, [EAIYAAPFAKKK], 20 µM
ATP, 10 µM
Assay Properties
Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (nM)
Staurosporine17
PP2162
AG1478580
D-644061,700
Scientific Information
P42684 (http://www.uniprot.org/uniprot/P42684)
Screening Location
Malvern, USA
Reference compound IC50 for ABL2/ARG
Reference compound IC50 for ABL2/ARG
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