ACE1 Protease Assay Service

ACE1 Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
ACE1
Enzyme
Human ACE1
Synonym
Angiotensin-converting enzyme, Dipeptidyl carboxypeptidase I, Kininase II, DCP, DCP1
Substrates
Fluorogenic peptide [MCA-RPPGFSAFK(Dnp)], 10 µM
Assay Properties
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (µM)
Captopril0.27
Scientific Information
P12821 (http://www.uniprot.org/uniprot/P12821)
Screening Location
Malvern, USA
Reference compound IC50 for ACE 1
Reference compound IC50 for ACE 1