ACVR2A Kinase Assay Service - Reaction Biology

Activity-based ACVR2A kinase assay for compound screening and profiling via radiometric HotSpot^TM kinase assay.

Target Overview

CAT#

ACVR2A

Enzyme

Human ACVR2A

HGNC

ACVR2A

Synonym

ACTR-IIA, ACTRIIA, ACVR2

Scientific Information

P27037 (http://www.uniprot.org/uniprot/P27037)

Assay Properties

Substrates

Casein, 20 µM
ATP, 10 µM

Reaction

Substrate + [γ-³³P]-ATP = ³³P-Substrate + ADP

Readout

Enzymatic activity

Reference Compound IC50s

Screening Location

Malvern, PA, USA

Reference compound inhibition of ACVR2A