Adam-10 Protease Assay Service

Adam-10 Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.

Target Overview
CAT#

Adam-10

Enzyme

Adam-10

Synonym

Disintegrin and metalloproteinase domain-containing protein 10, CDw156, Kuzbanian protein homolog, Mammalian disintegrin-metalloprotease, KUZ, MADM

Molecular Weight

52 kDa

Substrates

Fluorogenic substrate MCA-PLAQAV-Dpa-RSSSR-NH2, 10 µM

Assay Properties
Readout

Enzymatic activity

Reference Compound IC50s
Compounds IC50 (µM)
GM6001 0.526
Scientific Information

O14672 (https://www.uniprot.org/uniprotkb/O14672/entry)

Screening Location

Malvern, PA, USA

Further Information

More information can be found on our website Protease Assay Services

Reference compound IC50 for Adam-10

Reference compound IC50 for Adam-10