ALK2 (Q207D) Kinase Assay Service

Activity-based ALK2 (Q207D) kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview
CAT#
ALK2 (Q207D)/ACVR1
Enzyme
Human ALK2 (Q207D)/ACVR1
HGNC
ACVR1 (Q207D)
Synonym
ACTRI, ACVRLK2, ALK2, SKR1
Substrates
Casein, 20 µM
ATP 10 µM
Assay Properties
Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP
Readout
Enzymatic activity
Reference Compound IC50s
Scientific Information
Q04771 (http://www.uniprot.org/uniprot/Q04771)
Screening Location
Malvern, USA
Reference compound IC50 for ALK2 (Q207D)