ALK3/BMPR1A Kinase Assay Service

Activity-based ALK3/BMPR1A kinase assay for compound screening and profiling via radiometric HotSpot^TM kinase assay.

Target Overview

CAT#

ALK3/BMPR1A

Enzyme

Human ALK3/BMPR1A

HGNC

BMPR1A

Synonym

SKR5, CD292, ALK3, ACVRLK3

Substrates

Casein, 20 µM
ATP 10 µM

Assay Properties

Reaction

Substrate + [γ-³³P]-ATP = ³³P-Substrate + ADP

Readout

Enzymatic activity

Reference Compound IC50s

Scientific Information

P36894 (http://www.uniprot.org/uniprot/P36894)

Screening Location

Malvern, USA

Reference compound IC50 for ALK3/BMPR1A