ALK6/BMPR1B Kinase Assay Service

Activity-based ALK6/BMPR1B kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview
CAT#
ALK6
Enzyme
Human ALK6
HGNC
BMPR1B
Synonym
ALK6, CDw293
Substrates
Casein, 20 µM
ATP 10 µM
Assay Properties
Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (nM)
Staurosporine>100,000
Ro 31-8220>100,000
GW5074>100,000
Dorsomorphin340
LDN1931899.4
Scientific Information
O00238 (http://www.uniprot.org/uniprot/O00238)
Screening Location
Malvern, USA
Reference compound IC50 for ALK6/BMPR1B
Reference compound IC50 for ALK6/BMPR1B