AMPKalpha1 aa1-312 Kinase Activity Assay Service

Activity-based AMPKalpha1 aa1-312 kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology

Target Overview

RBE Target ID

AMPKalpha1 aa1-312

Enzyme

Human AMPKalpha1 aa1-312, wt

HGNC

PRKAA1 (aa1-312)

Manning ID

AMPKa1

Synonym

MGC33776, MGC57364, PRKAA1, AMPK-alpha1 aa1-312, AMPKalpha1 aa1-312, AMPKalpha1

UniProt

Q13131 (AAPK1_HUMAN)

Kinase Type

Protein kinase

Kinase Group

CAMK

Assay Properties

Assay Format

33PanQinaseTM

Substrates

RBER-CHKtide, ATP

Reaction

RBER-CHKtide + 33P-ATP = 33P-RBER-CHKtide + ADP

Readout

Enzymatic activity

Technical Reference Compound IC50 value(s)
Compounds IC50 (nM)
Staurosporine 14
Sorafenib 2700
Sunitinb 52

Screening Location

Freiburg, Germany

Further Information

More information can be found on our website Kinase Assays

Service and Product Availability

Screening Opportunities
FreeChoice AMPKalpha1 aa1-312
345 wt Profiler No
345 IC50 wt Profiler No
Mutant Profiler Addon No
Lipid Kinase Profiler Addon No
IC50 Profiler No
Recombinant Protein Availability
Active recombinant protein

Yes; ProQinaseTM – AMPKalpha1 aa1-312
(Activity verified by 33PanQinaseTM-Assay)

Product Number

0383-0000-1

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