ATAD2 Bromodomain Assay Service (AlphaScreen)

ATAD2-His Reader Domain Assay for compound screening and profiling using the AlphaScreen assay format to measure compound binding to the target.

Target Overview
CAT#

ATAD2-His

Enzyme

Human ATAD2-His

Synonyms

ATPase family AAA domain-containing protein 2, AAA nuclear coregulator cancer-associated protein, ANCCA, L16, PRO2000

Substrates

Histone H4 peptide (1-21) K5/8/12/16Ac

Assay Properties
Reaction

AlphaScreen Binding assay

Readout

Fluorescence

Reference Compound IC50s
Compounds IC50 (nM)
JQ-1 35,000
Bromosporine 89,000
SGC-CBP30 70,000
GSK2801 113,000
Scientific Information

Q6PL18 (http://www.uniprot.org/uniprot/Q6PL18)

Screening Location

Malvern, USA

Further information

More information can be found on our website Reader Domain Assay Services.

Reference Compound IC50 for ATAD2

Reference Compound IC50 for ATAD2