ATAD2B Bromodomain Assay Service (AlphaScreen)

ATAD2B-His Reader Domain Assay for compound screening and profiling using the AlphaScreen assay format to measure compound binding to the target.

Target Overview

CAT#

ATAD2B-His

Enzyme

Human ATAD2B-His

Synonyms

ATPase family AAA domain-containing protein 2B, KIAA1240

Substrates

Histone H4 peptide (1-21) K5/8/12/16Ac

Assay Properties

Reaction

AlphaScreen Binding assay

Readout

Fluorescence

Reference Compound IC50s
Compounds IC50 (nM)
JQ-1 125,000
PFI-1 >200,000
Bromosporine 103,000
SGC-CBP30 96,000

Scientific Information

Q9ULI0 (http://www.uniprot.org/uniprot/Q9ULI0)

Screening Location

Malvern, USA

Further information

More information can be found on our website Reader Domain Assay Services.

Reference Compound IC50 for ATAD2B

Reference Compound IC50 for ATAD2B