ATAD2B Bromodomain Assay Service (ThermoShift)

ATAD2B-His Reader Domain Assay for compound screening and profiling using the thermoshift assay format to measure compound binding to the target.

Target Overview



Human ATAD2B bromodomain, His-tagged


ATPase family AAA domain-containing protein 2B; KIAA1240

Assay Properties

Thermal stability change after ligand binding

Concentration of protein in assay

0.1 mg/ml (5.5 µM)

Concentration of compound in assay

25 µM

Apo form Tm (°C)


Reference Compound ΔTms:

No stabilization was observed in the presence of control compounds (JQ1, PFI1, CBP112, Bromosporine, SGC-CBP30, BET151, RVX-208, GSK2801 and PFI3)

Scientific Information

Q9ULI0 (

Screening Location

Malvern, USA

Further information

More information can be found on our website Reader Domain Assay Services.

Melt Curve

Melt Curve

Melt Peak

Melt Peak