Aurora C Kinase Assay Service

Activity-based Aurora C kinase assay for compound screening and profiling via radiometric HotSpot^TM kinase assay.

Target Overview

CAT#

Aurora C

Enzyme

Human Aurora C

HGNC

AURKC

Synonym

AurC, AIE2, AIK3, STK13

Substrates

Peptide substrate, [H-LRRASLG], 100 µM
ATP 10 µM

Assay Properties

Reaction

Substrate + [γ-³³P]-ATP = ³³P-Substrate + ADP

Readout

Enzymatic activity

Reference Compound IC50s

Scientific Information

Q9UQB9 (http://www.uniprot.org/uniprot/Q9UQB9)

Screening Location

Malvern, USA

Reference compound IC50 for Aurora C