BAZ1B Bromodomain Assay Service (AlphaScreen)

BAZ1B-His Reader Domain Assay for compound screening and profiling using the AlphaScreen assay format to measure compound binding to the target.

Target Overview

CAT#

BAZ1B-His

Enzyme

Human BAZ1B-His

Synonyms

Bromodomain adjacent to zinc finger domain protein 1B, hWALp2, WBSC10, WBSCR10, WBSCR9, WSTF

Substrates

Histone H4 peptide (1-21) K5/8/12/16Ac

Assay Properties

Reaction

AlphaScreen Binding assay

Readout

Fluorescence

Reference Compound IC50s
Compounds IC50 (nM)
JQ-1 21,000
SGC-CBP30 23,000
GSK2801 70,000

Scientific Information

Q9UIG0 (http://www.uniprot.org/uniprot/Q9UIG0)

Screening Location

Malvern, USA

Further information

More information can be found on our website Reader Domain Assay Services.

Reference Compound IC50 for BAZ1B

Reference Compound IC50 for BAZ1B