Activity-based BMP2K kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview
CAT#
BMP2K
Enzyme
Human BMP2K (38-345)
HGNC
BMP2K
Synonym
BMP-2-inducible protein kinase, BIKe
Scientific Information
Q9NSY1 (http://www.uniprot.org/uniprot/Q9NSY1)
Assay Properties
Substrates
AP2M1tide (SQITSQVTGQIGWRREG), 200 µM
ATP, 10 µM
Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP
Readout
Enzymatic activity
Reference Compound IC50s
Screening Location
Malvern, PA, USA
Further Information
More information can be found on our website Kinase Assays
Reference compound inhibition of BMP2K
