BMX/ETK Kinase Assay Service

Activity-based BMX/ETK kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview
CAT#
BMX
Enzyme
Human BMX
HGNC
BMX
Synonym
ETK, PSCTK2, PSCTK3
Substrates
Peptide substrate, poly[Glu:Tyr] (4:1), 0.2 mg/ml
ATP 10 µM
Assay Properties
Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (nM)
Staurosporine10
PP262
AG14787,400
D-6440614,000
Scientific Information
P51813 (http://www.uniprot.org/uniprot/P51813)
Screening Location
Malvern, USA
Reference compound IC50 for BMX/ETK
Reference compound IC50 for BMX/ETK