BPTF-[BRD]-His Reader Domain Assay for compound screening and profiling using the thermoshift assay format to measure compound binding to the target.
Human BPTF-[BRD] bromodomain, His-tagged
Bromodomain and PHD finger-containing transcription factor; FALZ; FAC1
Thermal stability change after ligand binding
0.075 mg/ml (4.2 µM)
No stabilization was observed in the presence of control compounds (JQ1, PFI1, CBP112, Bromosporine, SGC-CBP30, BET151, RVX-208, GSK2801 and PFI3)
More information can be found on our website Reader Domain Assay Services.