BRD1-GST Reader Domain Assay for compound screening and profiling using the thermoshift assay format to measure compound binding to the target.
Human BRD1 bromodomain, GST-tagged
BR140-like protein, BRL; Bromodomain and PHD finger-containing protein 2, BRPF-2
Thermal stability change after ligand binding
0.15 mg/ml (3.53 µM)
Bromosporine - 2.5 (Blue)No stabilization was observed in the presence of other control compounds (JQ1, PFI1, CBP112, SGC-CBP30, BET151, RVX-208, GSK2801 and PFI3)
More information can be found on our website Reader Domain Assay Services.