BRD1 Bromodomain Assay Service (AlphaScreen)

BRD1-His Reader Domain Assay for compound screening and profiling using the AlphaScreen assay format to measure compound binding to the target.

Target Overview
CAT#

BRD1

Enzyme

Human BRD1

Synonyms

Bromodomain-containing protein 1, BR140-like protein, Bromodomain and PHD finger-containing protein 2, BRL, BRPF2

Substrates

Histone H4 peptide (1-21) K5/8/12/16Ac

Assay Properties
Reaction

AlphaScreen Binding assay

Readout

Fluorescence

Reference Compound IC50s
Compounds IC50 (nM)
PFI-1 20,000
Bromosporine 1,700
Scientific Information

O95696 (http://www.uniprot.org/uniprot/O95696)

Screening Location

Malvern, USA

Further information

More information can be found on our website Reader Domain Assay Services.

Reference Compound IC50 for BRD1

Reference Compound IC50 for BRD1