BRD2-1-GST Reader Domain Assay for compound screening and profiling using the thermoshift assay format to measure compound binding to the target.
Human BRD2-1 bromodomain, GST-tagged
Thermal stability change after ligand binding
0.075 mg/ml (1.8 µM)
JQ1 - 4 (Orange)PFI1 - 3.5 (Pink)BET151 - 4.5 (Blue)No stabilization was observed in the presence of other control compounds (CBP112, SGC-CBP30, RVX-208, GSK2801 and PFI3)
More information can be found on our website Reader Domain Assay Services.