BRD2-2-GST Reader Domain Assay for compound screening and profiling using the thermoshift assay format to measure compound binding to the target.
Human BRD2-2 bromodomain, GST-tagged
Thermal stability change after ligand binding
0.07 mg/ml (1.7µM)
JQ1 - 2.5 (Orange)BET151 - 2 (Blue)No stabilization was observed in the presence of other control compounds (CBP112, SGC-CBP30, GSK2801 and PFI3)
More information can be found on our website Reader Domain Assay Services.