BRD3-1-His Reader Domain Assay for compound screening and profiling using the thermoshift assay format to measure compound binding to the target.
Human BRD3-1 bromodomain, His-tagged
Thermal stability change after ligand binding
0.085 mg/ml (5.0 µM)
JQ1 - 8.5 (Orange)PFI1 - 4.5 (Pink)BET151 - 9 (Blue)No stabilization was observed in the presence of other control compounds (CBP112, SGC-CBP30, RVX-208, GSK2801 and PFI3)
More information can be found on our website Reader Domain Assay Services.