BRD3-2-GST Reader Domain Assay for compound screening and profiling using the thermoshift assay format to measure compound binding to the target.
Human BRD3-2 bromodomain, GST-tagged
Thermal stability change after ligand binding
0.075 mg/ml (1.9 µM)
JQ1 - 4.5 (Orange)PFI1 - 3.5 (Pink)BET151 - 4.5 (Blue)RVX-208 - 2.5 (Purple)No stabilization was observed in the presence of other control compounds (CBP112, SGC-CBP30, GSK2801 and PFI3)
More information can be found on our website Reader Domain Assay Services.