BRD7-GST Reader Domain Assay for compound screening and profiling using the thermoshift assay format to measure compound binding to the target.
Human BRD7 bromodomain, GST-tagged
Thermal stability change after ligand binding
0.1 mg/ml (2.4 µM)
Bromosporine - 10.5 (Blue)RVX-208 - 2 (Purple)No stabilization was observed in the presence of other control compounds (JQ1, PFI1, BET151, GSK2801 and PFI3)
More information can be found on our website Reader Domain Assay Services.