BRD9-GST Reader Domain Assay for compound screening and profiling using the thermoshift assay format to measure compound binding to the target.
Human BRD9 bromodomain, GST-tagged
Rhabdomyosarcoma antigen MU-RMS-40.8
Thermal stability change after ligand binding
0.2 mg/ml (4.95 µM)
Bromosporine - 5.5 (Blue)No stabilization was observed in the presence of other control compounds (JQ1, PFI1, CBP112, BET151, GSK2801 and PFI3)
Scientific Information: Q9H8M2 (http://www.uniprot.org/uniprot/Q9H8M2)
More information can be found on our website Reader Domain Assay Services.