BRDT-1-His Reader Domain Assay for compound screening and profiling using the thermoshift assay format to measure compound binding to the target.
Human BRDT-1 bromodomain, His-tagged
CT9, RING3-like protein, BRD6
Thermal stability change after ligand binding
0.075 mg/ml (4.5 µM)
JQ1 - 3.5 (Orange)PFI1 - 1 (Pink)BET151 - 3.5 (Blue)No stabilization was observed in the presence of other control compounds (CBP112, SGC-CBP30, RVX-208, GSK2801, and PFI3)
More information can be found on our website Reader Domain Assay Services.