BRDT-2-His Reader Domain Assay for compound screening and profiling using the thermoshift assay format to measure compound binding to the target.
Human BRDT-2 bromodomain, His-tagged
CT9, RING3-like protein, BRD6
Thermal stability change after ligand binding
0.15 mg/ml (9.1 µM)
JQ1 - 8.5 (Orange)PFI1 - 4.5 (Pink)BET151 - 4 (Blue)RVX-208 - 1 (Purple)No stabilization was observed in the presence of other control compounds (CBP112, SGC-CBP30, GSK2801 and PFI3)
More information can be found on our website Reader Domain Assay Services.