BRPF1b-GST Reader Domain Assay for compound screening and profiling using the thermoshift assay format to measure compound binding to the target.
Human BRPF1b bromodomain, GST-tagged
Peregrin; Bromodomain and PHD finger-containing protein 1; BR140
Thermal stability change after ligand binding
0.1 mg/ml (2.5µM)
Bromosporine - 4.5 (Blue)PFI1 - 2 (Pink)RVX - 208 - 1.5 (Purple)No stabilization was observed in the presence of other control compounds (JQ1, CBP112, SGC-CBP30, BET151, GSK2801 and PFI3)
More information can be found on our website Reader Domain Assay Services.