BRSK2 Kinase Assay Service

Activity-based BRSK2 kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview
CAT#
BRSK2
Enzyme
Human BRSK2
HGNC
BRSK2
Synonym
C11orf7, FLJ41362, HUSSY-12, PEN11B, SAD1, STK29
Substrates
Peptide substrate, [KKLNRTLSFAEPG], 20 µM
ATP 10 µM
Assay Properties
Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (nM)
Staurosporine3.0
Ro 31-822077.6
GW 50746,300
H-89815
Scientific Information
Q8IWQ3 (http://www.uniprot.org/uniprot/Q8IWQ3)
Screening Location
Malvern, USA
Reference compound IC50 for BRSK2
Reference compound IC50 for BRSK2