BUB1B Kinase Activity Assay Service

Activity-based BUB1B kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology

Target Overview

RBE Target ID

BUB1B

Enzyme

Human BUB1B, wt

HGNC

BUB1B

Manning ID

BUBR1

Synonym

BUBR1, Bub1A, MAD3L, hBUBR1, BUB1B

UniProt

O60566 (BUB1B_HUMAN)

Kinase Type

Protein kinase

Kinase Group

Other

Assay Properties

Assay Format

33PanQinaseTM

Substrates

Casein, ATP

Reaction

Casein + 33P-ATP = 33P-Casein + ADP

Readout

Enzymatic activity

Technical Reference Compound IC50 value(s)
Compounds IC50 (nM)
Ceritinib 19000
Sorafenib 10000
Sunitinb 100000

Screening Location

Freiburg, Germany

Further Information

More information can be found on our website Kinase Assays

Service and Product Availability

Screening Opportunities
FreeChoice BUB1B
345 wt Profiler Yes
345 IC50 wt Profiler Yes
Mutant Profiler Addon No
Lipid Kinase Profiler Addon No
IC50 Profiler No
Recombinant Protein Availability
Active recombinant protein No
Product Number N/A
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