Calpain 1 Protease Assay Service

Calpain 1 Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.

Target Overview

CAT#

Calpain 1

Enzyme

Calpain 1

Synonym

Calcium-activated neutral proteinase 1, Calpain mu-type, Calpain-1 large subunit, Cell proliferation-inducing gene 30 protein, Micromolar calpain, CAN1, CAPN1, CANPL1

Substrates

Fluorogenic substrate N-Succinyl-LY-AMC, 10 µM

Assay Properties

Readout

Enzymatic activity

Reference Compound IC50s
Compounds IC50 (nM)
E-64 20.2

Scientific Information

P07384 (https://www.uniprot.org/uniprotkb/P07384/entry)

Screening Location

Malvern, PA, USA

Further Information

More information can be found on our website Protease Assay Services.

Reference compound IC50 for Calpain 1

Reference compound IC50 for Calpain 1