CAMK4 Kinase Assay Service

Activity-based CAMK4 kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview
CAT#
CAMK4
Enzyme
Human CAMK4
HGNC
CAMK4
Synonym
CaMK-GR, MGC36771
Substrates
Peptide substrate, [KKLNRTLSFAEPG], 20 µM
Ca2+-Calmodulin, 1 µM
ATP 10 µM
Assay Properties
Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP
Readout
Enzymatic activity
Reference Compound IC50s
Scientific Information
Q16566 (http://www.uniprot.org/uniprot/Q16566)
Screening Location
Malvern, USA
Reference compound IC50 for CAMK4