Caspase 10 Protease Assay Service

Caspase 10 Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
Caspase 10
Enzyme
Caspase-10, Highly active casp-10 from human cDNA, produced in an E. coli expression system (Residues Val 220 to Ile 479)
Synonym
CASP-10, ICE-like apoptotic protease 4, Apoptotic protease Mch-4, FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2
Substrates
(Z-LEHD)â‚‚-R110 tetrapeptide
Assay Properties
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (M)
Ac-IETD-CHO1.73E-06
Ac-VEID-CHO5.34E-07
Scientific Information
Q92851 (http://www.uniprot.org/uniprot/Q92851)
Screening Location
Malvern, USA
Reference compound IC50 for Caspase 10
Reference compound IC50 for Caspase 10