Caspase 1 Protease Assay Service

Caspase 1 Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
Caspase 1
Enzyme
Human Caspase 1
Synonym
Interleukin-1 beta convertase, p45, CASP1, IL1BC, IL1BCE
Substrates
Fluorogenic peptide [Ac-LEHD-AMC], 5 µM
Assay Properties
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (µM)
IETD-CHO0.33
Scientific Information
P29466 (http://www.uniprot.org/uniprot/P29466)
Screening Location
Malvern, USA
Reference compound IC50 for Caspase 1
Reference compound IC50 for Caspase 1