Caspase 2 Protease Assay Service

Caspase 2 Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
Caspase 2
Enzyme
Human Caspase 2
Synonym
Neural precursor cell expressed developmentally down-regulated protein 2, Protease ICH-1, CASP2, ICH1, NEDD2
Substrates
Fluorogenic peptide [Ac-LEHD-AMC], 5 µM
Assay Properties
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (µM)
IETD-CHO1.71
Scientific Information
P42575 (http://www.uniprot.org/uniprot/P42575)
Screening Location
Malvern, USA
Reference compound IC50 for Caspase 2
Reference compound IC50 for Caspase 2