Caspase 8 Protease Assay Service

Caspase 8 Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
Caspase 8
Enzyme
Human Caspase 8
Synonym
Apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, FADD-homologous ICE/ced-3-like protease, FADD-like ICE, ICE-like apoptotic protease 5, MORT1-associated ced-3 homolog, CASP8, MCH5
Substrates
Fluorogenic peptide [Ac-LEHD-AMC], 5 µM
Assay Properties
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (µM)
IETD-CHO0.018
Scientific Information
Q14790 (http://www.uniprot.org/uniprot/Q14790)
Screening Location
Malvern, USA
Reference compound IC50 for Caspase 8
Reference compound IC50 for Caspase 8