Cathepsin Z Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
Cathepsin Z
Enzyme
Human Cathepsin Z
Synonym
Cathepsin X, Cathepsin P
Assay Properties
Substrates
Mca-RPPGFSAFK(Dnp)-OH, 10 µM
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 (nM) |
|---|---|
| Chymostatin | 40.4 |
| E-64 | 49.5 |
| Leupeptin | 153.1 |
Scientific Information
Q9UBR2 (https://www.uniprot.org/uniprotkb/Q9UBR2/entry)
Screening Location
Malvern, PA, USA
Further Information
More information can be found on our website Protease Assay Services
Reference compound inhibition of Cathepsin Z
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