Cathepsin K Protease Assay Service

Cathepsin K Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview

CAT#
Cathepsin K

Enzyme
Human Cathepsin K

Synonym
CTSK, Cathepsin O/O2/X

Substrates
Fluorogenic peptide [Z-FR-AMC], 5 μM

Assay Properties

Readout
Enzymatic activity

Reference Compound IC50s
Compounds IC50 (nM)
E-64 0.37
Scientific Information
P43235 (http://www.uniprot.org/uniprot/P43235)

Screening Location
Malvern, USA