CBP Histone Acetyltransferase Assay Service

Activity-based CBP Histone Acetyltransferase Assay for compound screening and profiling via radiometric HAT assay.
CAT#
CBP
Enzyme
Human CBP
Synonyms
CREB-binding protein, CREBBP
Substrates
Histone H3, 5 μM
Acetyl CoA, 3 μM
Reaction
[Acetyl-³H]-Acetyl Coenzyme A + histone L-lysine = Coenzyme A + [Acety-³H]-L-lysine
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (nM)
Anacardic Acid20,000
Garcinol14,000
Curcumin37,000
Scientific Information
Q92793 (http://www.uniprot.org/uniprot/Q92793)
Screening Location
Malvern, USA
Reference Compound IC50 for CBP
Reference Compound IC50 for CBP
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