Activity-based CDK14/cyclin Y (PFTK1) kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview
CAT#
CDK14/Cyclin Y
Enzyme
Human CDK14/Cyclin Y
HGNC
CDK14/CCNY
Synonym
PFTAIRE1, PFTK1
Substrates
RB protein, 3 µM
ATP 10 µM
ATP 10 µM
Assay Properties
Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP
Readout
Enzymatic activity
Reference Compound IC50s
Scientific Information
Screening Location
Malvern, USA
Reference compound IC50 for CDK14 (PFTK1)/cyclin Y
![](https://www.reactionbiology.com/wp-content/uploads/2023/07/CDK14_cyclin_Y_PFTK1_Kin_Malvern.png)